Toe numbness and itching is a condition that belongs to the group of vitamin B2 deficiency diseases. This situation may present in various forms. However, most types of toe numbness and itching are typically accompanied by severe itching. To improve the itching symptoms, it is recommended to use oral Tabetil tablets, along with vitamin B2, to address any internal deficiencies. Additionally, apply topical Domeboro cream for comprehensive treatment. It’s also essential to avoid wearing damp, warm, and confined footwear daily to prevent the condition from worsening.