table of contents
◾ Overview
Athlete’s foot (tinea pedis) is a fungal infection affecting the skin of the feet, classified under infectious dermatological conditions. Its etiology is primarily linked to dermatophytes, necessitating antifungal interventions rather than antibacterial agents.
◾ Ineffective Treatments
❌ Thiosulphate:
While effective against bacterial infections (e.g., folliculitis, impetigo), thiosulphate lacks antifungal activity and is not indicated for athlete’s foot management.
◾ Recommended Therapies
🔹 Topical Antifungals
- Miconazole cream: Disrupts fungal cell membrane synthesis.
- Terbinafine cream: Inhibits squalene epoxidase, critical for fungal ergosterol production.
- Ketoconazole cream: Broad-spectrum azole antifungal.
🔹 Oral Antifungals (for severe/recurrent cases)
- Itraconazole: Triazole antifungal with systemic action.
- Terbinafine: Oral formulation for persistent infections.
◾ Clinical Considerations
- Diagnostic Confirmation: Microscopy or culture to differentiate from bacterial/eczematous conditions.
- Adjunctive Measures:
- Foot hygiene (keep dry, avoid occlusive footwear).
- Disinfect socks/shoes to prevent reinfection.
- Resistance Monitoring: Suspect treatment failure if symptoms persist beyond 2–4 weeks.
◾ Key Takeaway
Antifungal specificity is paramount. Misuse of antibacterial agents like thiosulphate delays resolution and increases recurrence risk.